By Sam Quinones
Kindle edition
P10 4%- "Later, I met other parents whose children were still alive, but who had shape-shifted into lying, thieving slaves to an unseen molecule. These parents feared each night the call that their child was dead in a McDonald’s bathroom"
I love this metaphor of being a slave to the "unseen molecule" and that this opiate molecule becomes a character in the story.
Pg 16 5% "The secretary put the letter in an envelope and sent it off to the prestigious New England Journal of Medicine, which, in due course, in its edition of January 10, 1980, published Dr. Jick’s paragraph on page 123 alongside myriad letters from researchers and physicians from around the country. It bore the title “Addiction Rare in Patients Treated with Narcotics.” With that, Hershel Jick filed the paragraph away and gave the letter scant thought for years thereafter. He published dozens of articles—including more than twenty in the NEJM alone. Jane Porter left the hospital and Dr. Jick lost track of her."
Little.did Dr Jick no it at the time, but this "paragraph" would be converted into a bonifide study but drug companies as they brought out more and more super-addictive and highly lucrative opiod based products to foist on an unsuspecting public.
Pg 25 8%
About the only new folks who came to Portsmouth then were merchants of the poor economy. Portsmouth got its first check-cashing places and its first rent-to-owns. Pawnshops and scrap metal yards opened. And David Procter expanded his practice.
The merchants of the poor economy yes. Read all about it in Gary Rivlin's Broke USA. There is big money in the poor.
Pg 25 8% "A new attitude was taking hold in American medicine at the time. The patient, it held, was always right, particularly when it came to pain. The doctor was to believe a patient who said he was in pain. David Procter embodied this new attitude, and then some. He had a folksy style, with a little of the evangelist in him."
I remember this change happening and thinking that it was overkill. They told us "pain is what the pt says it is." Then threatned us with legal action if we did not comply. The people pushing the hardest for this change were...you guessed it, the very same drug companies that made the drugs.
P35 9% "Valium became the pharmaceutical industry’s first hundred-million-dollar drug, and then its first billion-dollar drug. By the midseventies Valium was found indeed to be addictive and a street trade grew up around it."
Arthur Sackler and his new concept of drug advertisements and salesmen had struck gold and later in another decade he would do it again.
Pg 31 10% "But Arthur Sackler is important to this story because he founded modern pharmaceutical advertising and, in the words of John Kallir, showed the industry “that amazing things can be achieved with direct selling and intensive direct advertising.” Years later, Purdue would put those strategies to use marketing its new opiate painkiller OxyContin."
Pg 53 16% "In London in 1874, Dr. Alder Wright was attempting to find a nonaddictive form of morphine when he synthesized a drug that he called diacetylmorphine—a terrific painkiller. In 1898, a Bayer Laboratory chemist in Germany, Heinrich Dreser, reproduced Wright’s diacetylmorphine and called it heroin—for heroisch, German for “heroic,” the word that Bayer workers used to describe how it made them feel when Dreser tested it on them."
The ARC was shut down in the 1970s, when the U.S. Senate’s Church Committee, investigating the Central Intelligence Agency, found that the ARC had done experiments with LSD on inmates at the behest of the CIA. With that, an era ended. The Farm was transformed into the prison and hospital that it is today.
Pg 82 24% "Worldwide morphine consumption began to climb, rising thirtyfold between 1980 and 2011. But a strange thing happened. Use didn’t rise in the developing world, which might reasonably be viewed as the region in most acute pain. Instead, the wealthiest countries, with 20 percent of the world’s population, came to consume almost all—more than 90 percent—of the world’s morphine"
Pg84 25% "In 1984, Purdue Frederick produced one solution. It released MS Contin, a timed-release morphine pill—the product of that conversation Robert Twycross had with the Napp Pharmaceuticals reps in England years before. MS Contin was intended for cancer and postoperative patients."
Pg 91 27% "Initially, the market they sold to was older addicts like him—the heroin underworld that had survived since the 1970s, when the drug was last popular. But as it happened, illicit use of another drug—a pharmaceutical called OxyContin—was creating a vast new market for heroin among middle- and upper-class white people. Folks with money. When he heard about OxyContin, he began to follow it, knowing that if he did, he would soon have a market."
Pg 94 27% "An idea advanced that pain counteracted opiates’ euphoric effect and thus reduced the risk of addiction. In a statement on its website, the American Pain Society claimed that risk of addiction was low when opiates are used to treat patients in pain."
Wrong!!!
Pg 95 28% "We need to train doctors and nurses to treat pain as a vital sign.” The American Pain Society trademarked the slogan “Pain: The Fifth Vital Sign” and used it to promote the idea that doctors should attend to pain as routinely as to the other vital signs."
This was the beginning of the end. I remember when this change started happening and I remember thinking hmm this could be problematic.
In 1998, the Veterans Health Administration made pain a “fifth vital sign”—another gauge of a patient’s baseline health, along with pulse, blood pressure, body temperature, and respiration. The Joint Commission for Accreditation of Healthcare Organizations (JCAHO)—which accredits sixteen thousand health care organizations in the United States—did the same."
I was a nurse at the VA at this time and got a ring side seat.for start of the debacle. And JACHO? They are always quick to jump on any bandwagon that rolls by.
The California legislature required hospitals and nursing homes to screen for pain along with the other vital signs. The state’s Board of Pharmacy was by then assuring members that “studies show [opiates have] an extremely low potential for abuse” when used correctly."
Studies show? So far we have one speculative paragraph by Dr Jick and the biased Pourtenoy study from Sloan. Studies show huh? I hear that phrase alot at work when introducing some new misconception to my workplace. Ive learned over the years to get on the hip waders when I hear that term becuase that usually means the shit is about to get deep.
"In Tulsa, Oklahoma, two pediatric nurses—Donna Wong and her colleague, Connie Baker—sought a way of assessing pain in children who had trouble describing what they felt."
Patients are asked to quantify their pain according to a scale—numbered from 0 to 10, 10 being worst. These scales were highly subjective, but they were about the only pain-measurement tools medicine had to offer."
Subjective? Ya think?
Crucial implements in the revolution were Press Ganey surveys. Designed by a physician and a statistician, the surveys gauged patient satisfaction with their doctors. The surveys were a reasonable idea. They became widely used at U.S. hospitals in the 1990s as patient rights grew paramount and the JCAHO began aggressively measuring how hospitals treated patient pain."
Welcome to "Burger King" medicine. Have it your way at all costs even to the detriment of your own health...who was saying something about do no harm? Hmm
Through all this, patients were getting used to demanding drugs for treatment. They did not, however, have to accept the idea that they might, say, eat better and exercise more, and that this might help them lose weight and feel better."
Oh no. We never take responsibility for our own issues thats what i pay (or in most cases dont pay) you for.
[Im starting.to remember why i stopped using this awful program to take notes. It sucks
“The fifth vital sign” was a “concept, not a guide for pain assessment,” one report read. Along with the pain number scale, a doctor ought to ask numerous questions about a patient’s pain history, the pain’s location, severity, impact on daily life, as well as the patient’s family history, substance abuse, psychological issues, and so on. In fact, pain was really not a vital sign, after all, for unlike the four real vital signs it cannot be measured objectively and with exactitude."
Isnt that a lovely suit the Emperor is wearing.
“The way you’re reimbursed in a day, if you actually take the time to treat somebody’s pain, you’d be out of business,” one longtime family doc told me. “By the model you’re stuck in, you can’t do it. The hospital will get rid of you. If you’re by yourself, you can’t pay for your secretary.”
This is the elephant that no one wants to address. You want me to do all this good new stuff that studies show will help but i dont have time to. Like this doc above, if I actually did everything i was supposed to do i would be out of a job. They wouldnt pay the kind of overtime it would.rwquire to actually do what the plan requires.
These drugs were advertised mostly to primary care physicians, who had little pain-management training and were making their money by churning patients through their offices at a thirteen-minute clip. Not much time for nuance. Not much time for listening, or for open-ended questions that might elicit long and complicated answers."
Truer words have never been spoken. They tell you :heres what you do its easy" .but the plan has no basis in reality. The ones writing the plans have no clue what it actually takes to get this done in this bottom feeder mentality of health care today. Just talk to the pt they say. Get to know them. Then they tell you "oh by the way you are short a nuse again and theres no secretary and the pca is sitting. So good luck."
Years after his Pain paper, suggesting that pain patients treated with opiates might not be at risk of addiction, Portenoy said it was based on “weak, weak, weak data” and called it “a little paper [that] turned into an important paper.”
So much for that study.
By the 1990s, it would have alarmed Dr. Hershel Jick, out in Boston, to know that his letter to the editor of the New England Journal of Medicine, which he had long forgotten, had become a foundation for a revolution in U.S. medical practice. This was wildly beyond anything Herschel Jick intended when he penned it."
Wait a minute theres nothing to Jick either?
Hmm
That “less than 1 percent” statistic stuck. But a crucial point was lost: Jick’s database consisted of hospitalized patients from years when opiates were strictly controlled in hospitals and given in tiny doses to those suffering the most acute pain, all overseen by doctors. These were not chronic-pain patients going home with bottles of pain pills. It was a bizarre misinterpretation, for Jick’s letter really supported a contrary claim: that when used in hospitals for acute pain, and then when mightily controlled, opiates rarely produce addiction. Nevertheless, its message was transformed into that broad headline: “Addiction Rare in Patients Treated with Narcotics"
See how they run
A lot went into making it so. Porter and Jick appeared in that bible of scholarly and journalistic rectitude, the New England Journal of Medicine"
Ohh is that sarcasm
in 2010 did the NEJM put all its archives online; before that, the archives only went back to 1993. To actually look up Porter and Jick, to discover that it was a one-paragraph letter to the editor, and not a scientific study"
Yep one paragraph of musings
Everyone knew of opiates’ painkilling benefits. But how addictive were they? That was the question. Most doctors figured history and experience showed that the answer was: very. Porter and Jick, as it was cited, suggested otherwise. So did Dr. Portenoy: Depending on the patient, he believed, these drugs might be used to great advantage."
Use of opiates, meanwhile, changed medical thinking. Usually, a patient demanding ever-higher doses of a drug would be proof that the drug wasn’t working. But in opiate pain treatment, it was taken as proof that the doctor hadn’t yet prescribed enough. Indeed, some doctors came to believe that a pain patient demanding higher doses was likely to be exhibiting signs of “pseudoaddiction,” looking for a dose large enough to kill the pain—the cure for which was more opiates"
I gotta feva more cowbell
where OxyContin had already tenderized the terrain, sold not to tapped-out old junkies but to younger kids, many from the suburbs, most of whom had money and all of whom were white. Their transition from Oxy to heroin, he saw, was a natural and easy one. Oxy addicts began by sucking on and dissolving the pills’ timed-release coating. They were left with 40 or 80 mg of pure oxycodone. At first, addicts crushed the pills and snorted the powder. As their tolerance built, they used more. To get a bigger bang from the pill, they liquefied it and injected it. But their tolerance never stopped climbing. OxyContin sold on the street for a dollar a milligram and addicts very quickly were using well over 100 mg a day. As they reached their financial limits, many switched to heroin, since they were already shooting up Oxy and had lost any fear of the needle."
Pain Killer, Barry Meier
Books
American Night: The Literary Left in the Era of the Cold War.
By Alan Wald
David Courtwright Dark Paradise, history of opiate addiction in America.
William Burroughs Junky